SS-31 20mg – Research Peptide
Overview
This research-grade peptide is supplied exclusively for laboratory and experimental use. SS-31 is studied in experimental systems focused on mitochondrial stability, oxidative stress modulation, and cellular energy preservation. Research models examine its role in maintaining mitochondrial efficiency under stress conditions.
Primary mitochondrial research pairing
In experimental and laboratory research settings, SS-31 (Elamipretide) is examined either as a standalone mitochondrial-targeting compound or within specific growth hormone–related research models.
Growth hormone–related research context
Some experimental frameworks explore SS-31 alongside compounds involved in GHRH-mediated metabolic and mitochondrial signaling.
→ CJC-1295 (oral) – GHRH-related metabolic and mitochondrial signaling research
Alternative GH-axis research context
Other experimental models reference SS-31 in parallel with compounds studied for GH-axis modulation without long-acting GHRH analogs.
→ Tesamorelin – GH-axis and metabolic regulation research
→ Ipamorelin – GHRP-related energy and signaling research
Mitochondrial and cellular energy research context
In research frameworks not centered on growth hormone signaling, SS-31 is commonly examined alongside compounds involved in mitochondrial efficiency, cellular energy balance, and metabolic regulation.
→ SLU-PP-332 – mitochondrial energy signaling and metabolic efficiency research
Redox balance and metabolic cofactor research context
Some experimental discussions reference SS-31 alongside compounds examined for oxidative stress regulation and intracellular redox homeostasis.
→ L-Glutathione – antioxidant and redox signaling research
→ 5-Amino-1MQ – NNMT-related metabolic and NAD⁺ pathway research
Neurobiological and advanced signaling research context
In specialized experimental models, SS-31 may be referenced alongside compounds studied for neurotrophic signaling and synaptic function.
→ Dihexa – neurotrophic and synaptic signaling research
Alternative formulation and exposure models
Certain research discussions reference SS-31 alongside alternative peptide formats when evaluating delivery considerations and experimental exposure models.
→ BPC-157 (capsules) – comparative peptide format research
SS-31 Peptide, also known as elamipretide, MTP-131, or Bendavia, is a synthetic tetrapeptide that selectively targets and penetrates the inner mitochondrial membrane. Its unique structure allows it to bind cardiolipin, a critical phospholipid involved in maintaining mitochondrial structure and function. Research suggests that SS-31 pepptide can reduce mitochondrial oxidative damage, improve ATP production, and stabilize electron transport chain efficiency.
Studies have investigated SS-31 peptide in the context of age-related mitochondrial decline, cardiovascular dysfunction, neurodegeneration, and metabolic disorders, making it a promising compound in longevity and cellular health research.
SS-31 Peptide Research
Mitochondrial Protection:
- Binds and stabilizes cardiolipin to maintain mitochondrial cristae structure.
- Reduces production of reactive oxygen species (ROS), limiting oxidative damage.
Energy Metabolism:
- Enhances efficiency of oxidative phosphorylation, increasing ATP synthesis.
- Restores mitochondrial membrane potential in models of mitochondrial dysfunction.
Cardiovascular Studies:
- Improves cardiac bioenergetics and function in preclinical models of ischemia-reperfusion injury and heart failure.
Neuroprotection:
- Preserves mitochondrial function in neuronal cells, with potential benefits in neurodegenerative disease models.
Metabolic Health:
- Investigated for reversing age-associated declines in mitochondrial performance, potentially improving muscle endurance and metabolic flexibility.
SS-31 Peptide Product Description
- Sequence: D-Arg-Tyr(2,6-diMe)-Lys-Phe
- Molecular Formula: C₃₂H₄₉N₉O₅
- Molecular Weight: 639.8 g/mol
- PubChem CID: 11764719
- CAS Number: 736992-21-5
- Synonyms: elamipretide, MTP-131, Bendavia
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Total Active Ingredient: 20 mg per vial
Scientific background and research context:
→ SS-31 (Elamipretide): Mitochondrial function and energy research overview
Related research context
To explore how mitochondrial efficiency and metabolic signaling intersect with muscle performance and recovery research, see:
→ Muscle Growth & Regeneration: Research Perspectives
SS-31 Peptide Structures:

Source PubChem
Related research compounds:
→ NAD⁺ – Research-Grade Compound for mitochondrial energy metabolism
Product Usage
In vitro research or further manufacturing use only. Not for human or animal use.
Peptide Storage
All information provided by PRG is for educational and informational purposes only.
Best Practices for Storing Peptides
To maintain the reliability of laboratory results, correct peptide storage is essential. Proper storage conditions help preserve peptide stability for years while protecting against contamination, oxidation, and breakdown. Although certain peptides are more sensitive than others, following these best practices will greatly extend their shelf life and structural integrity.
- Short-Term Storage (days to months): Keep peptides cool and protected from light. Temperatures below 4 °C (39 °F) are generally suitable. Lyophilized peptides often remain stable at room temperature for several weeks, but refrigeration is still preferred if use is not immediate.
- Long-Term Storage (months to years): Store peptides at –80 °C (–112 °F) for maximum stability. Avoid frost-free freezers, as defrost cycles can cause damaging temperature fluctuations.
- Minimize Freeze–Thaw Cycles: Repeated freezing and thawing accelerates degradation. Instead, divide peptides into aliquots before freezing.
Preventing Oxidation & Moisture Damage
Peptides can be compromised by exposure to moisture and air—especially immediately after removal from a freezer.
- Let the vial warm to room temperature before opening to prevent condensation.
- Keep containers sealed as much as possible, and if possible, reseal under a dry, inert gas such as nitrogen or argon.
- Amino acids like cysteine (C), methionine (M), and tryptophan (W) are particularly sensitive to oxidation.
Storing Peptides in Solution
Peptides in solution have a much shorter lifespan compared to lyophilized form and are prone to bacterial degradation.
- If storage in solution is unavoidable, use sterile buffers at pH 5–6.
- Prepare single-use aliquots to avoid repeated freeze–thaw cycles.
- Most peptide solutions are stable for up to 30 days at 4 °C (39 °F), but sensitive sequences should remain frozen when not in use.
Containers for Peptide Storage
Select containers that are clean, intact, chemically resistant, and appropriately sized for the sample.
- Glass vials: offer clarity, durability, and chemical resistance.
- Plastic vials: polystyrene (clear but less resistant) or polypropylene (translucent but chemically resistant).
- Peptides shipped in plastic vials may be transferred to glass for long-term storage if desired.
Regenesis Peptide Storage Quick Tips
- Keep peptides in a cold, dry, dark environment
- Avoid repeated freeze–thaw cycles
- Minimize exposure to air
- Protect from light
- Avoid storing in solution long term
- Aliquot peptides to match experimental needs