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NAD+ – Research-Grade Compound (1000 mg)
€280,00
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Overview:
Nicotinamide adenine dinucleotide (NAD+) is a vital coenzyme found in every living cell, playing a central role in energy production, redox reactions, and cellular signaling. NAD+ supports mitochondrial efficiency, influences gene expression through sirtuin activation, and contributes to DNA repair. Research shows NAD+ levels decline with age, which may contribute to metabolic disorders, cognitive decline, and other age-related conditions. Supplementation aims to restore optimal levels, potentially improving resilience to oxidative stress and supporting overall cellular health.
Research:
Studies have demonstrated that NAD+ participates in critical oxidation–reduction reactions, acting as a cofactor for enzymes in glycolysis, the Krebs cycle, and oxidative phosphorylation. Beyond its metabolic role, NAD+ regulates signaling pathways involved in calcium homeostasis, inflammation, and chromatin remodeling. Declines in NAD+ during aging have been linked to increased oxidative stress, DNA damage, and mitochondrial dysfunction. This creates a cycle of metabolic decline, contributing to cellular senescence and impaired tissue function. Enhancing NAD+ availability has been shown to activate DNA repair enzymes, boost mitochondrial biogenesis, and improve metabolic performance in various models of aging and disease.
Further NAD⁺ Research Reading
For an in-depth overview of NAD⁺ biochemistry and its role in cellular energy metabolism, see our article What Is NAD⁺?, which examines the molecular mechanisms underlying NAD⁺ function in experimental research models.
To explore how NAD⁺ is studied in the context of aging-related pathways, autophagy, and cellular renewal, refer to our research overview on NAD⁺ and longevity research.
NAD+ Product Description:
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Synonyms: nadide, coenzyme I, beta-NAD, beta-nicotinamide adenine dinucleotide
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Molecular Formula: C21H27N7O14P2
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Molar Mass: 663.4 g/mol
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CAS Number: 53-84-9
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PubChem: 5892
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Total Amount of the Active Ingredient: 1000 mg (1 vial)
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Shelf Life: 36 months
NAD+ structure:
Source: PubMed
Related Metabolic Research Context
NAD⁺ is frequently studied in experimental models alongside compounds involved in metabolic regulation and NAD⁺-dependent signaling pathways. In preclinical research, small molecules such as 5-Amino-1MQ are investigated for their role in pathways that influence intracellular NAD⁺ availability, metabolic flux, and cellular energy balance.
Researchers examining NAD⁺ metabolism, redox regulation, and energy-related signaling may reference related research materials explored within these experimental frameworks.
Product Usage
This item is supplied for research purposes only.
Peptide Storage
All information provided by PRG is for educational and informational purposes only.
Best Practices for Storing Peptides
To maintain the reliability of laboratory results, correct peptide storage is essential. Proper storage conditions help preserve peptide stability for years while protecting against contamination, oxidation, and breakdown. Although certain peptides are more sensitive than others, following these best practices will greatly extend their shelf life and structural integrity.
- Short-Term Storage (days to months): Keep peptides cool and protected from light. Temperatures below 4 °C (39 °F) are generally suitable. Lyophilized peptides often remain stable at room temperature for several weeks, but refrigeration is still preferred if use is not immediate.
- Long-Term Storage (months to years): Store peptides at –80 °C (–112 °F) for maximum stability. Avoid frost-free freezers, as defrost cycles can cause damaging temperature fluctuations.
- Minimize Freeze–Thaw Cycles: Repeated freezing and thawing accelerates degradation. Instead, divide peptides into aliquots before freezing.
Preventing Oxidation & Moisture Damage
Peptides can be compromised by exposure to moisture and air—especially immediately after removal from a freezer.
- Let the vial warm to room temperature before opening to prevent condensation.
- Keep containers sealed as much as possible, and if possible, reseal under a dry, inert gas such as nitrogen or argon.
- Amino acids like cysteine (C), methionine (M), and tryptophan (W) are particularly sensitive to oxidation.
Storing Peptides in Solution
Peptides in solution have a much shorter lifespan compared to lyophilized form and are prone to bacterial degradation.
- If storage in solution is unavoidable, use sterile buffers at pH 5–6.
- Prepare single-use aliquots to avoid repeated freeze–thaw cycles.
- Most peptide solutions are stable for up to 30 days at 4 °C (39 °F), but sensitive sequences should remain frozen when not in use.
Containers for Peptide Storage
Select containers that are clean, intact, chemically resistant, and appropriately sized for the sample.
- Glass vials: offer clarity, durability, and chemical resistance.
- Plastic vials: polystyrene (clear but less resistant) or polypropylene (translucent but chemically resistant).
- Peptides shipped in plastic vials may be transferred to glass for long-term storage if desired.
Regenesis Peptide Storage Quick Tips
- Keep peptides in a cold, dry, dark environment
- Avoid repeated freeze–thaw cycles
- Minimize exposure to air
- Protect from light
- Avoid storing in solution long term
- Aliquot peptides to match experimental needs