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Tesamorelin (10 mg) + Ipamorelin (5 mg) Research Peptide Blend
€140,00
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Product Overview
The Tesamorelin (10 mg) + Ipamorelin (5 mg) Research Peptide Blend is a dual-component formulation designed for controlled laboratory investigations into growth hormone–related signaling pathways. Tesamorelin is a stabilized growth hormone–releasing hormone (GHRH) analog featuring enhanced structural resistance to enzymatic degradation, allowing extended receptor interaction in vitro. Ipamorelin is a selective agonist of the ghrelin receptor (GHSR-1a), known for its high receptor specificity and minimal off-target binding profile in experimental settings.
In combined format, this blend enables researchers to explore synergistic or comparative activation patterns involving GHRH-R and GHSR-1a pathways, providing a versatile model for studying intracellular signaling events, pulsatile GH modulation, peptide pharmacokinetics, and receptor-ligand dynamics.
Scientific Description
Tesamorelin is a synthetic, stabilized peptide analog of human GHRH incorporating modifications that increase half-life and promote sustained interaction with its receptor. Experimental models often assess its ability to modulate cAMP-dependent intracellular pathways, CREB-associated transcription factors, and somatotropic signaling cascades.
Ipamorelin, a pentapeptide secretagogue, selectively targets the GHSR-1a receptor without engaging secondary hormonal pathways. Its binding profile allows for the evaluation of ghrelin-mimetic receptor dynamics with minimized confounding cross-interactions seen in older GHRP-class compounds.
Together, Tesamorelin and Ipamorelin form a complementary dual-peptide system that supports advanced studies on coordinated receptor activation, downstream signal propagation, and peptide stability under controlled laboratory conditions.
Research Background
Scientific literature examining Tesamorelin and Ipamorelin frequently focuses on:
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Receptor synergy models: comparative and combined activation of GHRH-R and GHSR-1a pathways
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Pharmacokinetic analysis: stability, degradation kinetics, and extended plasma interaction modeling
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Intracellular signal mapping: cAMP-PKA, CREB, PLC, and calcium-dependent messenger pathways
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Growth hormone pulsatility simulations: rhythm modulation and receptor-driven pulse-pattern modeling
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Structure–activity relationships (SAR): amino acid modifications and their impact on receptor affinity and functional behavior
The 10 mg + 5 mg ratio is widely utilized in experimental settings due to its consistency and suitability for parallel or synergistic pathway evaluation.
Specifications & Identifiers
Tesamorelin 10 mg
Molecular Formula: C223H370N72O69S
Molar Mass: ~ 5196 g/mol
CAS Number: 901758-09-6
PubChem ID: 44147413
Total Active Ingredient: 10 mg lyophilised peptide per vial
Ipamorelin 5 mg
Synonyms: Ipamorelin, NNC-26-0161, Growth Hormone Secretagogue Pentapeptide
Molecular Formula: C₃₈H₄₉N₉O₅
Molar Mass: ~711.87 g/mol
CAS Number: 170851-70-4
PubChem CID: 9831659
Total Active Ingredient: 5 mg lyophilised peptide per vial
Product Usage
This item is supplied for research purposes only.
Peptide Storage
All information provided by PRG is for educational and informational purposes only.
Best Practices for Storing Peptides
To maintain the reliability of laboratory results, correct peptide storage is essential. Proper storage conditions help preserve peptide stability for years while protecting against contamination, oxidation, and breakdown. Although certain peptides are more sensitive than others, following these best practices will greatly extend their shelf life and structural integrity.
- Short-Term Storage (days to months): Keep peptides cool and protected from light. Temperatures below 4 °C (39 °F) are generally suitable. Lyophilized peptides often remain stable at room temperature for several weeks, but refrigeration is still preferred if use is not immediate.
- Long-Term Storage (months to years): Store peptides at –80 °C (–112 °F) for maximum stability. Avoid frost-free freezers, as defrost cycles can cause damaging temperature fluctuations.
- Minimize Freeze–Thaw Cycles: Repeated freezing and thawing accelerates degradation. Instead, divide peptides into aliquots before freezing.
Preventing Oxidation & Moisture Damage
Peptides can be compromised by exposure to moisture and air—especially immediately after removal from a freezer.
- Let the vial warm to room temperature before opening to prevent condensation.
- Keep containers sealed as much as possible, and if possible, reseal under a dry, inert gas such as nitrogen or argon.
- Amino acids like cysteine (C), methionine (M), and tryptophan (W) are particularly sensitive to oxidation.
Storing Peptides in Solution
Peptides in solution have a much shorter lifespan compared to lyophilized form and are prone to bacterial degradation.
- If storage in solution is unavoidable, use sterile buffers at pH 5–6.
- Prepare single-use aliquots to avoid repeated freeze–thaw cycles.
- Most peptide solutions are stable for up to 30 days at 4 °C (39 °F), but sensitive sequences should remain frozen when not in use.
Containers for Peptide Storage
Select containers that are clean, intact, chemically resistant, and appropriately sized for the sample.
- Glass vials: offer clarity, durability, and chemical resistance.
- Plastic vials: polystyrene (clear but less resistant) or polypropylene (translucent but chemically resistant).
- Peptides shipped in plastic vials may be transferred to glass for long-term storage if desired.
Regenesis Peptide Storage Quick Tips
- Keep peptides in a cold, dry, dark environment
- Avoid repeated freeze–thaw cycles
- Minimize exposure to air
- Protect from light
- Avoid storing in solution long term
- Aliquot peptides to match experimental needs