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CJC-1295 No DAC (10 mg) + Ipamorelin (5 mg) Research Peptide Blend
€140,00
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Product Overview
CJC-1295 + Ipamorelin is a dual-peptide blend commonly utilized in controlled experimental settings to investigate coordinated interactions within growth hormone–related signaling pathways. CJC-1295 is a synthetic tetrasubstituted peptide analog of GHRH, designed to support prolonged receptor engagement through increased stability. Ipamorelin is a selective GHSR (growth hormone secretagogue receptor) agonist frequently explored for its high receptor specificity and minimal off-target binding profile in laboratory assays.
Combined in a 10 mg (CJC-1295) + 5 mg (Ipamorelin) format, the blend enables researchers to examine multi-pathway activation dynamics involving both GHRH-mediated and ghrelin-mimetic mechanisms, offering a complementary model for studying pulsatile GH release patterns, receptor synergy, and peptide pharmacokinetics under controlled experimental conditions.
Scientific Description
CJC-1295 is a modified peptide incorporating Drug Affinity Complex (DAC) technology in some research variants, enhancing its plasma stability and receptor interaction time frame. It engages GHRH receptors (GHRH-R), influencing intracellular signaling cascades such as cAMP–PKA, CREB activation, and downstream transcriptional pathways related to somatotropic axis modulation.
Ipamorelin, a pentapeptide secretagogue, selectively binds GHSR-1a and exhibits high specificity for this receptor compared to earlier GHRP-class compounds. In vitro studies frequently evaluate its selective suppression of off-target hormones while maintaining preserved ghrelin-receptor binding kinetics. The combined blend allows investigation of synchronized receptor activation events, GH pulse frequency modulation, and comparative potency across peptide classes.
Research Background
Experimental literature involving CJC-1295 and Ipamorelin commonly focuses on:
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Receptor pathway synergy: GHRH-R and GHSR-1a co-activation and downstream signaling interplay.
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Pharmacokinetic modeling: comparative half-life, stability, and degradation kinetics of individual and combined peptides.
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Peptide–receptor binding profiles: selectivity, receptor affinity, and influence on intracellular messengers.
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Pulsatile secretion patterning: simulation and mapping of growth-hormone–related pulsatility in vitro.
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Structure–activity relationships (SAR): how substitutions and sequence motifs influence stability and function.
The blend format (10 mg + 5 mg) provides a practical ratio for comparative and combination-model research, enabling consistent experimental conditions across replicates.
Specifications & Identifiers
CJC-1295 - 10 mg
Molecular Formula: C₁₅₂H₂₅₂N₄₄O₄₂
Molar Mass: ~ 3367.9 g/mol
CAS Number: 863288-34-0
PubChem ID: 56841945
Total Active Ingredient: 10 mg lyophilised peptide per vial
Ipamorelin 5 mg
Synonyms: Ipamorelin, NNC-26-0161, Growth Hormone Secretagogue Pentapeptide
Molecular Formula: C₃₈H₄₉N₉O₅
Molar Mass: ~711.87 g/mol
CAS Number: 170851-70-4
PubChem CID: 9831659
Total Active Ingredient: 5 mg lyophilised peptide per vial
Product Usage
This item is supplied for research purposes only.
Peptide Storage
All information provided by PRG is for educational and informational purposes only.
Best Practices for Storing Peptides
To maintain the reliability of laboratory results, correct peptide storage is essential. Proper storage conditions help preserve peptide stability for years while protecting against contamination, oxidation, and breakdown. Although certain peptides are more sensitive than others, following these best practices will greatly extend their shelf life and structural integrity.
- Short-Term Storage (days to months): Keep peptides cool and protected from light. Temperatures below 4 °C (39 °F) are generally suitable. Lyophilized peptides often remain stable at room temperature for several weeks, but refrigeration is still preferred if use is not immediate.
- Long-Term Storage (months to years): Store peptides at –80 °C (–112 °F) for maximum stability. Avoid frost-free freezers, as defrost cycles can cause damaging temperature fluctuations.
- Minimize Freeze–Thaw Cycles: Repeated freezing and thawing accelerates degradation. Instead, divide peptides into aliquots before freezing.
Preventing Oxidation & Moisture Damage
Peptides can be compromised by exposure to moisture and air—especially immediately after removal from a freezer.
- Let the vial warm to room temperature before opening to prevent condensation.
- Keep containers sealed as much as possible, and if possible, reseal under a dry, inert gas such as nitrogen or argon.
- Amino acids like cysteine (C), methionine (M), and tryptophan (W) are particularly sensitive to oxidation.
Storing Peptides in Solution
Peptides in solution have a much shorter lifespan compared to lyophilized form and are prone to bacterial degradation.
- If storage in solution is unavoidable, use sterile buffers at pH 5–6.
- Prepare single-use aliquots to avoid repeated freeze–thaw cycles.
- Most peptide solutions are stable for up to 30 days at 4 °C (39 °F), but sensitive sequences should remain frozen when not in use.
Containers for Peptide Storage
Select containers that are clean, intact, chemically resistant, and appropriately sized for the sample.
- Glass vials: offer clarity, durability, and chemical resistance.
- Plastic vials: polystyrene (clear but less resistant) or polypropylene (translucent but chemically resistant).
- Peptides shipped in plastic vials may be transferred to glass for long-term storage if desired.
Regenesis Peptide Storage Quick Tips
- Keep peptides in a cold, dry, dark environment
- Avoid repeated freeze–thaw cycles
- Minimize exposure to air
- Protect from light
- Avoid storing in solution long term
- Aliquot peptides to match experimental needs