This research-grade peptide combination is supplied exclusively for laboratory and experimental use. The Ipamorelin and Tesamorelin combination is studied in experimental systems examining complementary growth hormone–related signaling pathways. Research models explore how pulsatile and regulatory endocrine signals interact within metabolic and structural adaptation frameworks.
The Tesamorelin (10 mg) + Ipamorelin (5 mg) Research Peptide Blend is a dual-component formulation designed for controlled laboratory investigations into growth hormone–related signaling pathways. Tesamorelin is a stabilized growth hormone–releasing hormone (GHRH) analog featuring enhanced structural resistance to enzymatic degradation, allowing extended receptor interaction in vitro. Ipamorelin is a selective agonist of the ghrelin receptor (GHSR-1a), known for its high receptor specificity and minimal off-target binding profile in experimental settings.
In combined format, this blend enables researchers to explore synergistic or comparative activation patterns involving GHRH-R and GHSR-1a pathways, providing a versatile model for studying intracellular signaling events, pulsatile GH modulation, peptide pharmacokinetics, and receptor-ligand dynamics.
Tesamorelin is a synthetic, stabilized peptide analog of human GHRH incorporating modifications that increase half-life and promote sustained interaction with its receptor. Experimental models often assess its ability to modulate cAMP-dependent intracellular pathways, CREB-associated transcription factors, and somatotropic signaling cascades.
Ipamorelin, a pentapeptide secretagogue, selectively targets the GHSR-1a receptor without engaging secondary hormonal pathways. Its binding profile allows for the evaluation of ghrelin-mimetic receptor dynamics with minimized confounding cross-interactions seen in older GHRP-class compounds.
Together, Tesamorelin and Ipamorelin form a complementary dual-peptide system that supports advanced studies on coordinated receptor activation, downstream signal propagation, and peptide stability under controlled laboratory conditions.
Scientific literature examining Tesamorelin and Ipamorelin frequently focuses on:
Receptor synergy models: comparative and combined activation of GHRH-R and GHSR-1a pathways
Pharmacokinetic analysis: stability, degradation kinetics, and extended plasma interaction modeling
Intracellular signal mapping: cAMP-PKA, CREB, PLC, and calcium-dependent messenger pathways
Growth hormone pulsatility simulations: rhythm modulation and receptor-driven pulse-pattern modeling
Structure–activity relationships (SAR): amino acid modifications and their impact on receptor affinity and functional behavior
The 10 mg + 5 mg ratio is widely utilized in experimental settings due to its consistency and suitability for parallel or synergistic pathway evaluation.
Tesamorelin 10 mg
Molecular Formula: C223H370N72O69S
Molar Mass: ~ 5196 g/mol
CAS Number: 901758-09-6
PubChem ID: 44147413
Total Active Ingredient: 10 mg lyophilised peptide per vial
Ipamorelin 5 mg
Synonyms: Ipamorelin, NNC-26-0161, Growth Hormone Secretagogue Pentapeptide
Molecular Formula: C₃₈H₄₉N₉O₅
Molar Mass: ~711.87 g/mol
CAS Number: 170851-70-4
PubChem CID: 9831659
Total Active Ingredient: 5 mg lyophilised peptide per vial
Este item é fornecido exclusivamente para fins de investigação.
Todas as informações fornecidas pela PRG destinam-se apenas a fins educativos e informativos.
Para manter a fiabilidade dos resultados laboratoriais, o armazenamento correto dos peptídeos é essencial. Condições adequadas ajudam a preservar a estabilidade dos peptídeos durante anos, protegendo-os contra contaminação, oxidação e degradação.
Embora alguns peptídeos sejam mais sensíveis do que outros, seguir estas boas práticas prolongará significativamente a vida útil e a integridade estrutural.
Os peptídeos podem ser comprometidos pela exposição à humidade e ao ar, especialmente após a remoção do congelador.
Os peptídeos em solução têm uma vida útil muito mais curta do que na forma liofilizada e são mais suscetíveis à degradação bacteriana.
Selecionar recipientes limpos, intactos, quimicamente resistentes e adequados ao volume da amostra.
Peptídeos enviados em frascos de plástico podem ser transferidos para vidro para armazenamento a longo prazo, se desejado.
