{"product_id":"ahk-cu-100-mg","title":"AHK-Cu 100 mg – Hair Follicle Research Peptide (Roller Format)","description":"\u003ch3\u003eAHK-Cu (Copper Tripeptide-3) – Overview and Structure\u003c\/h3\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003eAHK-Cu (Alanine–Histidine–Lysine Copper), also known as Copper Tripeptide-3, is a synthetic copper-binding tripeptide complex composed of alanine, histidine, and lysine coordinated with a copper (Cu²⁺) ion.\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003eCAS No.: 682809-81-0 (HCl form)  \u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003eMolecular weight: ~415–451 Da  \u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003eAHK-Cu is studied as a targeted analog of naturally occurring copper peptides, with particular relevance in research models involving hair follicle biology and dermal papilla cell (DPC) signaling.\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003eThe peptide structure enables stable chelation of Cu²⁺ through histidine and peptide backbone interactions, forming a coordinated complex that supports controlled intracellular copper transport and enzyme-related functions.\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003c\/div\u003e\n\u003ch3 dir=\"ltr\"\u003eMolecular Mechanism of Action (Research Context)\u003c\/h3\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003eAHK-Cu is studied as both a signaling peptide and a bioavailable copper carrier within cellular systems.\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003eIn experimental models, it is associated with pathways relevant to dermal papilla cell activity, including:\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e• cellular proliferation signaling  \u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e• apoptosis-related pathway modulation  \u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e• growth factor–related signaling pathways  \u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e• copper-dependent enzymatic processes  \u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003eThese pathways are explored in relation to hair follicle cycling, particularly mechanisms associated with the anagen (growth) phase.\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003cstrong\u003eAHK-Cu is also studied for its interaction with:\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e• VEGF-related signaling (angiogenesis pathways)  \u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e• TGF-β–associated regulatory pathways  \u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e• intracellular antioxidant enzyme systems  \u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003eCopper delivered via the peptide complex is associated with enzyme cofactor activity, including systems linked to oxidative balance and extracellular matrix dynamics.\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003c\/div\u003e\n\u003ch3 dir=\"ltr\"\u003eHair Follicle Research and Cellular Models\u003c\/h3\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003eAHK-Cu is frequently examined in in vitro and ex vivo models of hair follicle biology.\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003eResearch observations associate the compound with:\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e• dermal papilla cell signaling activity  \u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e• follicular structure dynamics in organ culture models  \u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e• cellular environment interactions within the hair follicle niche  \u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003eThese mechanisms are studied in relation to follicle size, structural integrity, and growth-phase signaling pathways.\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003c\/div\u003e\n\u003ch3 dir=\"ltr\"\u003eSkin and Cellular Research Context\u003c\/h3\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003eIn addition to follicle-related pathways, AHK-Cu is also examined in broader skin-related models.\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003eThese include:\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e• fibroblast activity  \u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e• collagen-related pathways  \u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e• extracellular matrix interactions  \u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e• cellular regeneration signaling  \u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003eThis positions AHK-Cu as a compound of interest in both hair-focused and dermal research environments.\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003c\/div\u003e\n\u003ch3 dir=\"ltr\"\u003eComparative Research Overview\u003c\/h3\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e\n\u003ctable style=\"width: 100%;\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22.4638%;\"\u003e  \u003cstrong\u003eProperty\u003c\/strong\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 40.6304%;\"\u003e\u003cstrong\u003eAHK-Cu (Copper Tripeptide-3)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 36.0001%;\"\u003e\u003cstrong\u003eGHK-Cu (Copper Tripeptide-1)\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22.4638%;\"\u003e Sequence\u003c\/td\u003e\n\u003ctd style=\"width: 40.6304%;\"\u003eAla-His-Lys-Cu²⁺\u003c\/td\u003e\n\u003ctd style=\"width: 36.0001%;\"\u003eGly-His-Lys-Cu²⁺ \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22.4638%;\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd style=\"width: 40.6304%;\"\u003e682809-81-0\u003c\/td\u003e\n\u003ctd style=\"width: 36.0001%;\"\u003e49557-75-7\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22.4638%;\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd style=\"width: 40.6304%;\"\u003e~415–451 Da\u003c\/td\u003e\n\u003ctd style=\"width: 36.0001%;\"\u003e~340–404 Da\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22.4638%;\"\u003eOrigin\u003c\/td\u003e\n\u003ctd style=\"width: 40.6304%;\"\u003eSynthetic analog\u003c\/td\u003e\n\u003ctd style=\"width: 36.0001%;\"\u003eNaturally occurring peptide\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22.4638%;\"\u003ePrimary Research Focus\u003c\/td\u003e\n\u003ctd style=\"width: 40.6304%;\"\u003eHair follicle \/ DPC models\u003c\/td\u003e\n\u003ctd style=\"width: 36.0001%;\"\u003eBroad skin-related pathways\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22.4638%;\"\u003eMechanistic Focus\u003c\/td\u003e\n\u003ctd style=\"width: 40.6304%;\"\u003eDPC signaling, pathway modulation\u003c\/td\u003e\n\u003ctd style=\"width: 36.0001%;\"\u003eFibroblast signaling, ECM pathways\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22.4638%;\"\u003eHair Research Relevance\u003c\/td\u003e\n\u003ctd style=\"width: 40.6304%;\"\u003eHigh\u003c\/td\u003e\n\u003ctd style=\"width: 36.0001%;\"\u003eModerate\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22.4638%;\"\u003eSkin Research Relevance\u003c\/td\u003e\n\u003ctd style=\"width: 40.6304%;\"\u003eSecondary\u003c\/td\u003e\n\u003ctd style=\"width: 36.0001%;\"\u003ePrimary \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 22.4638%;\"\u003eResearch Context\u003c\/td\u003e\n\u003ctd style=\"width: 40.6304%;\"\u003eIn vitro \/ ex vivo follicle studies\u003c\/td\u003e\n\u003ctd style=\"width: 36.0001%;\"\u003eExtensive skin-related models\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch3 dir=\"ltr\"\u003eResearch Applications and Context\u003c\/h3\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003eAHK-Cu is studied in experimental systems focusing on:\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e• hair follicle biology  \u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e• dermal papilla cell signaling  \u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e• copper-dependent enzyme activity  \u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e• angiogenesis-related pathways  \u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e• extracellular matrix regulation  \u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003eIt is frequently included in research exploring targeted peptide delivery systems and localized cellular signaling environments.\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003c\/div\u003e\n\u003ch3 dir=\"ltr\"\u003eSummary\u003c\/h3\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003eAHK-Cu (Copper Tripeptide-3) is a synthetic copper-binding peptide studied in relation to hair follicle biology, dermal papilla cell signaling, and copper-dependent cellular pathways.\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003eIts mechanisms are associated with:\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e• cellular signaling and proliferation pathways  \u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e• growth factor–related systems  \u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e• antioxidant and enzymatic processes  \u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e• extracellular matrix interactions  \u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003eThese properties make it a relevant compound in research focused on localized cellular environments and peptide-mediated signaling systems.\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003eAll information provided reflects research-based observations in experimental models and is intended for scientific and educational purposes.\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv dir=\"ltr\"\u003e\n\u003ch3 style=\"margin-bottom: 0cm;\"\u003eDelivery System and Format (Research Context)\u003c\/h3\u003e\n\u003cp style=\"margin-bottom: 0cm;\"\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp style=\"margin-bottom: 0cm;\"\u003eThis product is presented as a roller-based peptide delivery system integrating AHK-Cu within a manual applicator format.\u003c\/p\u003e\n\u003cp style=\"margin-bottom: 0cm;\"\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp style=\"margin-bottom: 0cm;\"\u003eThe device features a 64-pin roller head with ultra-fine 0.5 mm gold-tipped titanium needles and an integrated reservoir system designed to hold the peptide solution within the applicator structure.\u003c\/p\u003e\n\u003cp style=\"margin-bottom: 0cm;\"\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0908\/7113\/6522\/files\/ahk_roll_1.png?v=1777385167\"\u003e\u003c\/p\u003e\n\u003cp style=\"margin-bottom: 0cm;\"\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp style=\"margin-bottom: 0cm;\"\u003eIn experimental and cosmetic research settings, microneedle-based systems are studied for their ability to create controlled micro-scale surface channels, allowing localized interaction between peptide compounds and the surrounding skin environment.\u003c\/p\u003e\n\u003cp style=\"margin-bottom: 0cm;\"\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp style=\"margin-bottom: 0cm;\"\u003eThe roller format is associated with uniform distribution across the application surface and consistent contact between the peptide solution and targeted areas in controlled models.\u003c\/p\u003e\n\u003cp style=\"margin-bottom: 0cm;\"\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp style=\"margin-bottom: 0cm;\"\u003eThe device operates mechanically without the need for external power sources and is constructed using materials selected for stability and compatibility in topical research environments.\u003c\/p\u003e\n\u003cp style=\"margin-bottom: 0cm;\"\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp style=\"margin-bottom: 0cm;\"\u003eGold-tipped titanium components are commonly used in such systems due to their structural properties and surface characteristics in repeated-contact applications.\u003c\/p\u003e\n\u003cp style=\"margin-bottom: 0cm;\"\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0908\/7113\/6522\/files\/ahk_roll_2.png?v=1777385167\"\u003e\u003c\/p\u003e\n\u003cp style=\"margin-bottom: 0cm;\"\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp style=\"margin-bottom: 0cm;\"\u003eThis format is examined in research exploring localized peptide delivery, surface interaction dynamics, and controlled distribution systems.\u003c\/p\u003e\n\u003cp style=\"margin-bottom: 0cm;\"\u003e \u003c\/p\u003e\n\u003cp style=\"margin-bottom: 0cm;\"\u003eThis section describes the delivery format and presentation of the product within experimental and cosmetic research contexts.\u003c\/p\u003e\n\u003cp style=\"margin-bottom: 0cm;\"\u003e \u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"PRG","offers":[{"title":"Default Title","offer_id":52941068599562,"sku":null,"price":190.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0908\/7113\/6522\/files\/AHK-cu100mg_2.png?v=1777624563","url":"https:\/\/www.peptideregenesis.com\/products\/ahk-cu-100-mg","provider":"PRG","version":"1.0","type":"link"}